Skip to main content

Below is a list of software available on BisonNet. Most software packages are added and removed from your environment using Environment Modules (e.g. module load matlab). If you need additional software, please submit a request by emailing bisonnet@bucknell.edu.

Also, some software packages have specific instructions that are necessary to follow.

SoftwareVersionDescriptionModule
admixture1.3.0A software tool for maximum likelihood estimation of individual ancestries from multilocus SNP genotype datasets.admixture
augustus3.5.0Predicts genes in eukaryotic genomic sequencesassembly_assessment
avogadro21.100A free and open source molecular editor and visualization tool.avogadro2
bamtools2.5.2Manipulate BAM (genetic sequence) filesassembly_assessment
BBTools35.85BBTools is a suite of fast, multithreaded bioinformatics tools designed for analysis of DNA and RNA sequence dataassembly_assessment
BCFTools1.21BCFtools is a program for variant calling and manipulating files in the Variant Call Format (VCF) and its binary counterpart BCFbcftools
bedtools22.31.1Manipulate bed format filesseq_tools
BLAST2.2.26BLAST finds regions of similarity between biological sequences. Note that this is the legacy C tookit BLAST and should only be used as required by other programs. Generally, most people should use BLAST+, which is part of the ncbi-blast module.blast
bowtie22.5.4Map reads to a reference genomealignment (python/3.12-bio)
Bracken3.0.1Bayesian Reestimation of Abundance with KrakENkraken2
Braker33.0.8BRAKER is a pipeline for fully automated prediction of protein coding gene structures with GeneMark-ES/ET/EP/ETP and AUGUSTUS in novel eukaryotic genomesbraker3
BUSCO5.8.3Measures quality of assemblyassembly_assessment (python/3.12-bio)
canu2.3A single molecule sequence assembler for genomes large and small.
assembly
chromap0.2.7Fast alignment and preprocessing of chromatin profilesgenome
COMSOL Multiphysics6.3A finite element analysis, solver and multiphysics simulation softwarecomsol
CUDA12.6.3The NVIDIA® CUDA® Toolkit provides a development environment for creating high performance GPU-accelerated applications.cuda
cudnn9.8.0The NVIDIA CUDA® Deep Neural Network library (cuDNN) is a GPU-accelerated library of primitives for deep neural networks.cudnn
dfam-tetools2025.03.26Dfam Transposable Element Tools singularity container
dfam-tetools
dvr-scan1.7Find and extract motion events in videos.python/3.10-misc
emacs30.1GNU Emacs editoremacs
EMBOSS6.6.0Manipulating sequence files, among other thingsseq_tools
EVidence Modeler2.1.0The EVidenceModeler (aka EVM) software combines ab intio gene predictions and protein and transcript alignments into weighted consensus gene structuresannotation
exonerate2.4.0Exonerate is a generic tool for pairwise sequence comparisonexonerate (python/3.12-bio)
fasta-splitter.pl0.2.7Split FASTA filesseq_tools
fastp0.24.0A tool designed to provide fast all-in-one preprocessing for FastQ files.fastp,qc
fastQC0.12.1To assess the quality of DNA sequence dataqc
fastx_toolkit0.0.14To perform basic manipulations on DNA sequence dataqc
ffmpeg7.1AV conversion toolsffmpeg
funannotate1.8.5Funannotate is a genome prediction, annotation, and comparison software packagepython/3.12-bio
Gaussian16.B.01Computational chemistrygaussian
gcc/g++/gfortran11.5.0Open source compiler collection(none required)
GCTA1.94.3Genome-wide Complex Trait Analysisseq_tools
glimmer3.02Glimmer is a system for finding genes in microbial DNA, especially the genomes of bacteria, archaea, and viruses.glimmer
gmap-gsnap2024-11-20GMAP: A Genomic Mapping and Alignment Program for mRNA and EST Sequences, and
GSNAP: Genomic Short-read Nucleotide Alignment Program
alignment
GT-POWER2025.1.0001GT-POWER is used to predict engine performance quantities such as power, torque, airflow, volumetric efficiency, fuel consumption, turbocharger performance and matching, and pumping losses, to name just a few.GT-POWER
Gurobi Optimizer12.0.1An optimization solver for linear programming (LP), quadratic programming (QP), quadratically constrained programming (QCP), mixed integer linear programming (MILP), mixed-integer quadratic programming (MIQP), and mixed-integer quadratically constrained programming (MIQCP)gurobi-optimizer
HISAT22.2.1graph-based alignment of next generation sequencing reads to a population of genomesalignment
hmmer3.4Used for searching sequence databases for sequence homologs and for making sequence alignmentsassembly_assessment
HTStream1.3.0Quality control pipeline for High Throughput Sequencing dataqc
IBAMR0.16An adaptive and distributed-memory parallel implementation of the immersed boundary (IB) method(not a module)
ILOG CPLEX Studio22.1.2A mathematical optimization software packageCPLEX
insectOR2024.05.09This package helps to annotate genes coding for any specific family of proteins from a medium sized genomeinsectOR
ipyrad0.9.104Assembly and analysis of RAD-seq type genomic data setsradseq (python/3.12-bio)
iqtree2.4.0Build phylogenetic trees from sequencesphylogeny
I-TASSER5.2Iterative Threading ASSEmbly RefinementI-TASSER
JDFTx1.7.0JDFTx is a plane-wave density-functional theory (DFT) code designed to be as easy to develop with as it is easy to use.jdftx
jellyfish2.3.1Tool for fast, memory-efficient counting of k-mers in DNAalignment
jmodeltest22.1.10Find the best model of sequence evolution for building phylogeniesphylogeny
kallisto0.51.1Map reads to a reference genome (without sketchiness)alignment
Kraken22.1.4A taxonomic classification systemkraken2
LAMMPS2024.08.29LAMMPS is a classical molecular dynamics code with a focus on materials modeling.lammps
MAFFT7.471Align sequencesmafft
Maker3.01.03MAKER is a portable and easily configurable genome annotation pipeline.annotation
Mathematica14.2.1A modern technical computing system spanning most areas of technical computing — including neural networks, machine learning, image processing, geometry, data science, visualizations, and others.mathematica
MatlabR2024bMulti-paradigm numerical computing environment and programming languagematlab
metaeuk7.0Sensitive, high-throughput gene discovery, and annotation for large-scale eukaryotic metagenomicsassembly_assessment
minimap22.28A versatile pairwise aligner for genomic and spliced nucleotide sequencesgenome
MrBayes3.2.7Building phylogeniesphylogeny
MultiQC1.28Aggregate results from bioinformatics analyses across many samples into a single reportpython/3.12-bio
ncbi-BLAST+2.16.0+BLAST alignment to database. $NCBI_DATA set to top-level of weekly database downloads.ncbi-blast
NextPolish1.4.1Fast and accurately polish the genome generated by long reads.genome
octave9.4.0Powerful mathematics-oriented syntax with built-in 2D/3D plotting and visualization toolsoctave
Omni-C2025.03.25The Dovetail™ Omni-C™ library uses a sequence-independent endonuclease for chromatin digestion prior to proximity ligation and library generation.Omni-C
OpenCV4.11.0Open source Computer Visionopencv
openmpi5.0.7Message Passing Interface project, generally used for running parallel code.openmpi
ORCA6.0.1ORCA is a powerful and versatile quantum chemistry software package.orca
PAL2NAL14.1Force nucleotides onto protein alignmentsalignment (python/3.12-bio)
PAML4.10.7Testing genes for selectionmolecular_evolution
PASTEC2025.04.11Singularity image for PASTEC (transposable elements classification tool).repeats
Perl5.40.1General purpose programming languageperl
PfamScan1.6PfamScan is used to search a FASTA sequence against a library of Pfam HMM.pfamscan
plink1.9PLINK is a free, open-source whole genome association analysis toolsetplink
prodigal2.6.3Prodigal Gene Prediction Softwareassemsbly_assessment
purge_dups1.2.6haplotypic duplication identification toolgenome
Python3.12General purpose programming languagepython
pysam0.22.1Pysam is a Python module for reading and manipulating SAM/BAM/VCF/BCF files.python/3.12-bio
PySPH1.0b2.dev0A framework for Smoothed Particle Hydrodynamics in Pythonpython/3.10-misc
R4.4.3Software environment for statistical computing and graphicsR
RELION5.0relion (for REgularised LIkelihood OptimisatioN, pronounce rely-on) is a software package that employs an empirical Bayesian approach for electron cryo-microscopy (cryo-EM) structure determination.RELION
RSEM1.3.3Calculates read counts from BAM filesalignment
salmon1.10.0Map reads to a reference genome (wicked fast)alignment
samtools1.16.1Manipulate sam and bam filesseq_tools,genome
Scaff10X5.0Pipeline for scaffolding and breaking a genome assembly using 10x genomics linked-readsassembly
seqtk1.4Toolkit for processing sequences in FASTA/Q formatsseq_tools
SIMULIA2025Software suite, including Abaqus and Tosca, for finite element analysis and computer-aided engineeringSIMULIA
SOAP DeNovor242Assembling genomesassembly
SRA_Toolkit3.2.1Downloads files from the Sequence Read Archiveseq_tools
stacks2.68Stacks is a software pipeline for building loci from short-read sequences, such as those generated on the Illumina platformstacks
STAR2.7.11bMap reads to a reference genomealignment
structure2.3.4A free software package for using multi-locus genotype data to investigate population structure.structure
TEClass2.1.3bClassification of TE consensus sequencesrepeats
TOGA1.1.7TOGA (Tool to infer Orthologs from Genome Alignments): implements a novel paradigm to infer orthologous genes.genome
TopHat2.1.1TopHat is a fast splice junction mapper for RNA-Seq reads.alignment
TransDecoder5.7.1Identifies candidate coding regions within transcript sequencestransdecoder
Trimmomatic0.39To trim bad quality sequence dataqc
Trinity2.15.2For transcriptome assemblyTrinity
vcflib1.0.13

C++ library and cmdline tools for parsing and manipulating VCF files with python and zig bindingspython/3.12-bio
vcftools0.1.16C++ library and cmdline tools for parsing and manipulating VCF files with python and zig bindingsseq_tools
VEP113.4Variant Effect Predictorseq_tools
Visual Studio Code1.100.3Integrated development environmentvscode
wtgbg22.5A fuzzy Bruijn graph approach to long noisy reads assemblygenome
XCrySDen1.6.2XCrySDen is a crystalline and molecular structure visualisation programxcrysden
xmgrace5.1.252D plotting toolxmgrace
yahs1.2.2Yet another Hi-C scaffolding toolgenome